When study patients are exposed to Ora’s CAE® (Controlled Adverse Environment) Dry Eye Challenge in terms of relative humidity, temperature, airflow, and visual tasking, the ocular surface is stressed to react. This controlled environmental stress creates a consistent response that’s reproducible over time. Data derived from the CAE® model offers greater precision in predicting the efficacy of your drug – with fewer patients, fewer sites, and less time.
The Ora CAE®Dry Eye Challenge creates the ideal paradigm for identifying:
We provide a menu of trial designs within the context of CAE®: from traditional endpoints, to CAE® model patient screening and enrichment, to a full CAE® trial with screening/patient enrichment and CAE®-specific endpoints of dry eye disease. We work with you to determine the right approach for your product.
Our Mobile Dry Eye Units enable multi-center dry eye trials while still reducing clinical variables among sites. With Ora, you can bring your clinical trial to the patient.
The Ora CAE® Model can be: