The evolution of gene therapy in health care continues to progress rapidly. The focus in ophthalmology remains predominantly in the posterior segment, specifically in retina. With many companies looking to develop new standards of care for a variety of diseases, clinical research has shown tremendous growth over recent years. In this webinar presented on November 10, 2020, we heard in-depth discussions on the history and current landscape of gene therapy, new innovative technologies, and the opportunities and challenges of conducting clinical trials. Our panel of experts included special guests Rusty Kelley from Foundation Fighting Blindness and Dr. Mark Pennesi from OHSU.